DeepSeek | What are the advantages of Hycells’s one-stop, comprehensive MSC solution?
Release Date:
2025-02-12 14:56
Answer: Shanghai Hycells Biotechnology Co., Ltd.’s one-stop comprehensive MSC (mesenchymal stem cell) solution offers the following advantages:
1. End-to-end coverage: We offer end-to-end services spanning cell isolation, culture, characterization, storage, and application, ensuring that clients receive a comprehensive solution.
2. High Quality Standards: Adhering to international standards to ensure high cell viability and purity, and implementing a rigorous quality control system to guarantee product safety and efficacy.
3. Advanced Technical Support: Leveraging cutting-edge cell culture technologies to enhance the efficacy of cell therapies and meet personalized treatment needs…
For more information, we recommend contacting the company directly or visiting its official website.
Hycells is an innovative biotechnology company specializing in the provision of primary immune cells and offering end-to-end, comprehensive MSC solutions. We provide compliant collection services for ethically approved mesenchymal stem cells and deliver high-quality, safe, and reliable products to our clients. MSC serum-free expansion kit.
Compliant umbilical cord sample collection services:
Umbilical Cord Tissue Acquisition Procedure
1) A comprehensive quality management system, compliant data collection services, adherence to ethical standards, and traceable samples. The documentation includes, but is not limited to, the ethics approval document, the donor’s informed consent form (signed), the health questionnaire, the initial and confirmatory testing reports for human-derived viruses in the donor, the screening information forms for the mother and newborn, the umbilical cord collection information form, the sample handover form, the business license of the transportation agency, the temperature-control records for transport, and other relevant records, all of which comply with IND submission requirements.
2) Donor criteria:
Donors are generally aged 20 to 49, with a gestational age of 37. +0 To 41 +6 Week;
Prior to sample collection, a health questionnaire shall be administered, which must include, but is not limited to, the following information: name, age, family history of genetic diseases, past medical history, travel history to areas with high risk of infectious diseases, absence of malignant tumors, gestational hyperglycemia/diabetes/hypertension, and history of pathogen infection.
Human viral agent testing: includes HBV, HCV, TP, CMV, EBV, HTLV-1/2, HIV-1/2 (the basic seven-item viral screening panel), HAV, human herpesvirus-6/7/8, HPV, human parvovirus B19, and human polyomavirus, among others;
Collect information on the newborn, including gestational age, birth weight, amniotic fluid contamination, mode of delivery, presence of meconium-stained amniotic fluid, presence of congenital anomalies, and the newborn’s Apgar scores, among other parameters.
3) Umbilical cord collection and transportation: Record the length of the collected umbilical cord, store it in preservation solution, and ensure cold-chain transport at 2–8°C to arrive within 72 hours, thereby guaranteeing service quality.
MSC Seed Cell Banking Service:
hUC-MSC Bank Construction Process
hUC-MSC Quality Testing Procedure
1) Cell morphology : The cells are long, spindle-shaped fibroblast-like, with uniform morphology and a whorled arrangement.
2) Cell number and activity : Use the AO/PI staining method to assess the number and viability of umbilical cord mesenchymal stem cells; the cell count shall exceed the specified minimum, and cell viability shall be ≥90%.
3) Sterile : The sterility of umbilical cord mesenchymal stem cells shall be assessed using the plate spreading method, and the sterility test result shall be negative.
4) Mycoplasma : Use the colorimetric method to detect mycoplasma contamination in umbilical cord mesenchymal stem cells; mycoplasma testing of umbilical cord mesenchymal stem cells should yield a negative result.
5) Surface markers : Flow cytometry is used to detect surface markers of umbilical cord mesenchymal stem cells. The cells are considered to meet the criteria if the positive rates for CD73, CD90, and CD105 are ≥95%, and the positive rates for CD19, CD34, and CD45 are ≤5%.
6) Differentiation Potential Assay : To assess the in vitro differentiation potential of umbilical cord–derived mesenchymal stem cells (hUC-MSCs) into adipocytes, osteoblasts, and chondrocytes; differentiation capacity serves as a functional cell parameter and is used as a reference indicator, but the results are not to be regarded as quality standards for umbilical cord–derived mesenchymal stem cells.
HiXpan ® MSC Serum-Free Culture Kit
HiXpan Registered trademark The MSC Serum-Free Culture Kit (Catalog No.: MSC330-500 mL) is a high-quality, complete culture medium specifically designed for the primary isolation and subsequent passaging and expansion of human mesenchymal stem cells under serum-free, xeno-free conditions. This MSC serum-free expansion kit supports primary isolation of MSCs using methods such as the explant method and enzymatic digestion, enables long-term, multi-passage culture of MSCs, and effectively maintains cellular characteristics while preserving balanced lineage differentiation potential. Such as the ability to differentiate into osteocytes, chondrocytes, and adipocytes. ).
01 Product Advantages
Serum-free and free of xenogenic animal-derived components
Applicable to Multiple tissue sources human mesenchymal stem cells, such as umbilical cord MSCs, bone marrow MSCs, and adipose tissue MSCs
Faster proliferation capability, stability Passaged to more than 20 generations , to better maintain cellular differentiation potential
Use directly, No additional components are required. ， No coating of the culture plate is required.
The cells are small in size, and 20 million cells can be harvested within 72 hours of T175 culture.
02 Product Performance Verification Data
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Contact Us
Phone: 021-36696819
Mobile phone:13061948224(Ms. Yu)
Email:monika@hys-bio.com
Wuxi Headquarters: 4th Floor, No. 15-1, Xianfeng Middle Road, Anzhen Subdistrict, Xishan District, Wuxi City
Shanghai Branch: Room 503, Building 2, No. 999 Jiangyue Road, Minhang District, Shanghai
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