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29

2024-01

2023 Year-End Summary | Breaking the Mold, Fostering Innovation

回首2023，是逆势破局，砥砺前进 展望2024，是笃行不怠，赓续前行 新的一年，我们将继续满怀热忱，共赴山海

2024-01-29

He Yousheng

19

2024-01

Exhibition Recap | Collaboration & Symbiosis

The COVID-19 pandemic has thrust mRNA vaccines into the global spotlight, disrupting the long-standing dominance of first-generation live attenuated and inactivated vaccines as well as second-generation subunit vaccines worldwide and paving the way for the iterative advancement of third-generation vaccines. mRNA vaccines offer numerous advantages, including rapid development, high safety, robust immune protection, and efficient manufacturing, thereby opening up new avenues for the prevention and control of infectious diseases. Moreover, mRNA holds tremendous potential for applications in immunotherapy, antibody and protein replacement therapies, cell therapy, regenerative medicine, gene editing, and gene therapy delivery systems.

2024-01-19

He Yousheng

29

2023-12

Gathering in Suzhou | 2024 xRNA Nucleic Acid Drug Development and Innovation Forum

The development of nucleic acid therapeutics has been marked by numerous ups and downs, but it has ultimately borne fruit, with widespread applications in the treatment of genetic diseases, cancers, viral infections, and other conditions. Small nucleic acid drugs offer distinct advantages, including rapid target identification, high success rates in drug discovery and development, a low propensity for resistance, broader therapeutic coverage, and prolonged efficacy. mRNA vaccines have also advanced rapidly in the context of the COVID-19 pandemic. With the maturation of in vitro mRNA synthesis and delivery technologies, the stability and translational efficiency of mRNA therapeutics have improved substantially, with the bulk of current applications concentrated in the vaccine sector. Moreover, mRNA holds tremendous potential for use in immunotherapy, protein replacement therapy, cell therapy, regenerative medicine, and other fields. According to projections, the global mRNA market is expected to reach US$23 billion by 2035.

2023-12-29

He Yousheng

21

2023-11

Hycells Recruitment | Continuous Exploration and Innovation

Shanghai University is a comprehensive university under the jurisdiction of the Shanghai Municipal Government. It is a key institution designated for China’s “Double First-Class” initiative and the national “Project 211,” as well as one of the first batch of high-level local universities in Shanghai and a model institution for deepening reform in innovation and entrepreneurship education.

2023-11-21

He Yousheng

09

2023-11

New Product Trial | More Convenient and Efficient IL-15 NK Cell Expansion Reagent (Stromal Cells)

Immunotherapy is currently one of the most promising approaches for cancer treatment, with natural killer (NK) cells emerging as particularly promising effector cells. Immune cells are broadly categorized into adaptive and innate components. Innovative therapeutics targeting adaptive immune cells include cytotoxic T lymphocytes (CTLs), tumor-infiltrating lymphocytes (TILs), chimeric antigen receptor T cells (CAR-T cells), and T-cell receptors engineered T cells (TCR-T cells). Among these, CAR-T therapy is currently the most actively pursued modality; however, following CAR-T cell infusion, patients may experience two major severe adverse effects: cytokine release syndrome and neurotoxicity. Although CAR-T therapy achieves high rates of complete remission, it is associated with immune cell exhaustion, which can lead to disease relapse, and its efficacy against solid tumors remains limited due to off-target effects.

2023-11-09

He Yousheng

31

2023-10

Hycells Birthday Party | Love and Peace

Quarterly birthday celebrations have become a cherished tradition for our team, providing the perfect opportunity to come together, shake off the stresses and strains of daily work, and create a haven where both body and mind can find rest and rejuvenation.

2023-10-31

He Yousheng
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