Sample Service
Recommended Information
CD4+ Naive T Cell Sorting Service
CD14+ Monocyte Sorting Service
Monocytes are the largest blood cells and the largest type of white blood cell, playing a crucial role in the body’s defense system. They originate from hematopoietic stem cells in the bone marrow and continue to mature there; however, they remain immature cells when they enter the bloodstream. Monocytes also participate in immune responses by phagocytosing antigens and then presenting antigenic epitopes to lymphocytes, thereby inducing specific immune responses in these cells. Furthermore, monocytes constitute a major cellular defense mechanism against intracellular pathogenic bacteria and parasites and possess the ability to recognize and kill tumor cells. Compared with other blood cells, monocytes contain higher levels of nonspecific esterases and exhibit more robust phagocytic activity. Alterations in the percentage of monocytes can occur in response to inflammation or other diseases; therefore, monitoring monocyte counts is an important adjunctive diagnostic tool.
CD19 is a CD molecule (i.e., a leukocyte differentiation antigen) expressed by B cells, belonging to the immunoglobulin superfamily and possessing two immunoglobulin-like domains. It is a single-chain glycoprotein found on the surface of B lymphocytes and follicular dendritic cells in the hematopoietic system. All B-cell lineages except plasma cells, as well as malignant B cells and FDCs, express this molecule. CD19 is an important membrane antigen involved in B-cell proliferation, differentiation, activation, and antibody production, and it also facilitates BCR signal transduction. As a key biomarker, CD19 is widely used in research on chimeric antigen receptor T-cell (CAR-T) therapy and antibody–drug conjugates (ADCs).
Natural killer cells (NK cells) are the third major class of lymphocytes, alongside T cells and B cells. They are involved not only in antitumor immunity, antiviral defense, and immune regulation, but also in the pathogenesis of hypersensitivity reactions and autoimmune diseases.
NTreg Natural Regulatory T Cell Sorting Service
Regulatory T cells (Tregs) are a subset of T cells that modulate autoimmune reactivity within the body and play a crucial role in maintaining immune tolerance. They are generated in the thymus, then exported to the peripheral tissues, where they actively suppress the activation and proliferation of potentially autoreactive T cells present in healthy individuals, thereby regulating immune responses and preventing the development of autoimmune diseases.
Irradiated PBMCs: Acting as trophoblast-like cells, they provide a variety of essential cytokines for the activation and expansion of TILs, as well as for the activation and expansion of NK cells.
Human Genetic Management Consulting Services
It is prohibited for foreign organizations, individuals, and institutions established or effectively controlled by them to collect, preserve, or provide China’s human genetic resources to entities outside China.